Т. В. Поспелова

Часть публикаций из профиля, по году от новых к старым. Это не полный список последних работ автора; работы без года — в конце.

• The bibliometric analysis of regional innovations of Kazakhstan in the context of Triple Helix model2024
• Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells2022
• Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases2018
• Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway2017
• G1 checkpoint is compromised in mouse ESCs due to functional uncoupling of p53-p21Waf1 signaling2015
• Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers2014
• Cyclin-dependent kinase inhibitor p21Waf1: Contemporary view on its role in senescence and oncogenesis2012 · аннотациясвернуть

  p21(Waf1) was identified as a protein suppressing cyclin E/A-CDK2 activity and was originally considered as a negative regulator of the cell cycle and a tumor suppressor. It is now considered that p21(Waf1) has…

• p21Waf1is required for cellular senescence but not for cell cycle arrest induced by the HDAC inhibitor sodium butyrate2010 · аннотациясвернуть

  Cell senescence is characterized by senescent morphology and permanent loss of proliferative potential. HDAC inhibitors (HDACI) induce senescence and/or apoptosis in many types of tumor cells. Here, we studied the role…