Т. В. Поспелова
Высшая школа экономики
- Telomeres, Telomerase, and Senescence
- Histone Deacetylase Inhibitors Research
- Cancer-related Molecular Pathways
- Epigenetics and DNA Methylation
- Autophagy in Disease and Therapy
Чем занимается
Ключевые темы по публикациям: Telomeres, Telomerase, and Senescence; Histone Deacetylase Inhibitors Research; Cancer-related Molecular Pathways; Epigenetics and DNA Methylation; Autophagy in Disease and Therapy.
Последние работы
Все 78 в OpenAlexRapamycin decelerates cellular senescence2009 · аннотациясвернуть
When the cell cycle is arrested but cellular growth is not, then cells senesce, permanently losing proliferative potential. Here we demonstrated that the duration of cell cycle arrest determines a progressive loss of…
Cyclin-dependent kinase inhibitor p21Waf1: Contemporary view on its role in senescence and oncogenesis2012 · аннотациясвернуть
p21(Waf1) was identified as a protein suppressing cyclin E/A-CDK2 activity and was originally considered as a negative regulator of the cell cycle and a tumor suppressor. It is now considered that p21(Waf1) has…
Activation of DNA damage response signaling in mouse embryonic stem cells2008 · аннотациясвернуть
Mouse embryonic stem cells (mESC) are characterized by high proliferation activity. mESC are highly sensitive to genotoxic stresses and do not undergo G(1)/S checkpoint upon DNA-damage. mESC are supposed to develop…
p21Waf1is required for cellular senescence but not for cell cycle arrest induced by the HDAC inhibitor sodium butyrate2010 · аннотациясвернуть
Cell senescence is characterized by senescent morphology and permanent loss of proliferative potential. HDAC inhibitors (HDACI) induce senescence and/or apoptosis in many types of tumor cells. Here, we studied the role…
- Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers2014
- The bibliometric analysis of regional innovations of Kazakhstan in the context of Triple Helix model2024
- Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells2022
- Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases2018
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Шаблон письма
Здравствуйте, Т. В. Поспелова! Я студент(ка) [курс, факультет, вуз]. Мне интересна тема [опишите интересы своими словами]. Прочитал(а) вашу работу «Rapamycin decelerates cellular senescence» (2009) — она близка к тому, чем я хочу заниматься. Хочу обсудить возможность выполнить научную работу под вашим руководством. Буду благодарен(на) за ответ — готов(а) рассказать о себе подробнее и прислать резюме. С уважением, [Имя Фамилия]
На этапе теста письмо отправляешь сам из своей почты. Отправка из сервиса и статусы заявок — скоро.