A.A. Eldeeb

Часть публикаций из профиля, по году от новых к старым. Это не полный список последних работ автора; работы без года — в конце.

• Antisense Oligonucleotide Releasing Cassette for Conditional Targeted RNA Degradation2026
• Tripled‐Stranded Antisense Oligonucleotide for Biomarker‐Activated Suppression of Essential Genes2026
• A Binary DNAzyme Machine (BDM) for Selective Amplification-Free Detection of microRNA2026
• Dual‐Stage Mismatch Interrogation (DMI) for High‐Fidelity G–T Discrimination by a DNA Nanodevice2026
• Multivalent DNAzyme agents for cleaving folded RNA2024 · аннотациясвернуть

  Multivalent recognition and binding of biological molecules is a natural phenomenon that increases the binding stability (avidity) without decreasing the recognition specificity. In this study, we took advantage of this…

• Towards the development of a DNA automaton: modular RNA-cleaving deoxyribozyme logic gates regulated by miRNAs2024
• DNAzyme Nanomachine with Fluorogenic Substrate Delivery Function: Advancing Sensitivity in Nucleic Acid Detection2023 · аннотациясвернуть

  We have developed a hook-equipped DNA nanomachine (HDNM) for the rapid detection of specific nucleic acid sequences without a preamplification step. HDNM efficiently unwinds RNA structures and improves the detection…

• Binary Antisense Oligonucleotide Agent for Cancer Marker-Dependent Degradation of Targeted RNA2022 · аннотациясвернуть

  Antisense oligonucleotide technology is one of the most successful gene therapy (GT) approaches. However, low selectivity of antisense agents limits their application as anticancer drugs. To achieve activation of…